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Original article

Vol. 152 No. 2526 (2022)

Hospital incidence and mortality of patients treated for abdominal aortic aneurysms in Switzerland – a secondary analysis of Swiss DRG statistics data

  • Lorenz Meuli
  • Anna-Leonie Menges
  • Klaus Steigmiller
  • Andreas Kuehnl
  • Benedikt Reutersberg
  • Ulrike Held
  • Alexander Zimmermann
DOI
https://doi.org/10.4414/SMW.2022.w30191
Cite this as:
Swiss Med Wkly. 2022;152:w30191
Published
27.06.2022

Summary

AIM OF THE STUDY: To analyse hospital incidence and in-hospital mortality of patients treated for abdominal aortic aneurysms in Switzerland.

METHODS: Secondary data analysis of case-related hospital discharge data of the Swiss Federal Statistical Office for the years 2009–2018. Patients who were hospitalised and surgically treated for nonruptured abdominal aortic aneurysms or hospitalised and treated for ruptured abdominal aortic aneurysms were included in the analysis. Standardised annual incidences rates were calculated using the European standard population 2013. In-hospital all-cause mortality rates were calculated as raw values and standardised for age, sex, and the van Walraven comorbidity score.

RESULTS: A total of 10,728 cases were included in this study, of which 87.1% were male. Overall, 22.7% of the patients presented with a ruptured abdominal aortic aneurysm; 46% of these cases were surgically treated whereas 54% received conservative therapy. The age-standardised cumulative hospital incidences for treatment of nonruptured abdominal aortic aneurysms were 2.6 (95% confidence interval 2.5–2.8) and 19.7 (19.2–20.1) per 100,000 for women and men, respectively; for ruptured aneurysms it was 0.4 (0.3–2.4) per 100,000 in women, and 2.7 (2.6–2.9) in men. The annual incidence rates were stable in the decade observed. The adjusted mortality rates for treatment of nonruptured aneurysms decreased from 5.5% (2.6–11.2%) in 2009 to 1.4% (0.5–3.6%) in 2018 in women, and from 2.4% (1.3–4.5%) in 2009 to 0.6% (0.2–1.5%) in 2018 in men. The adjusted mortality rates for treatment of ruptured abdominal aortic aneurysms remained high without relevant improvements for either sex over time: for women 32.4% (24.1–42.1%), for men 19.7% (16.8–22.8%).

CONCLUSIONS: The hospital incidence rates for nonruptured and ruptured abdominal aortic aneurysms remained unchanged in the decade observed. Compared with Germany, there was no evidence for a decrease in the annual incidence rates for ruptured abdominal aortic aneurysms in Switzerland. Mortality rates in the elective setting were low and decreased in the last decade but remained high in patients treated for ruptured aneurysms. Efforts to reduce the incidence of ruptured abdominal aortic aneurysms are needed to reduce aneurysm-related mortality in Switzerland.

References

  1. Mani K, Lees T, Beiles B, Jensen LP, Venermo M, Simo G, et al. Treatment of abdominal aortic aneurysm in nine countries 2005-2009: a vascunet report. Eur J Vasc Endovasc Surg. 2011 Nov;42(5):598–607. https://doi.org/10.1016/j.ejvs.2011.06.043
  2. Anjum A, Powell JT. Is the incidence of abdominal aortic aneurysm declining in the 21st century? Mortality and hospital admissions for England & Wales and Scotland. Eur J Vasc Endovasc Surg. 2012 Feb;43(2):161–6. https://doi.org/10.1016/j.ejvs.2011.11.014
  3. Mani K, Björck M, Wanhainen A. Changes in the management of infrarenal abdominal aortic aneurysm disease in Sweden. Br J Surg. 2013 Apr;100(5):638–44. https://doi.org/10.1002/bjs.9046
  4. Schermerhorn ML, Bensley RP, Giles KA, Hurks R, Oʼmalley AJ, Cotterill P, et al. Changes in abdominal aortic aneurysm rupture and short-term mortality, 1995-2008: a retrospective observational study. Ann Surg. 2012 Oct;256(4):651–8. https://doi.org/10.1097/SLA.0b013e31826b4f91
  5. Kühnl A, Erk A, Trenner M, Salvermoser M, Schmid V, Eckstein H-H. Incidence, Treatment and Mortality in Patients with Abdominal Aortic Aneurysms. Deutsches Aerzteblatt Online. 2017 Jun 5;
  6. Wanhainen A, Verzini F, Van Herzeele I, Allaire E, Bown M, Cohnert T, et al.; Esvs Guidelines Committee. Editor’s Choice - European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms. Eur J Vasc Endovasc Surg. 2019 Jan;57(1):8–93. https://doi.org/10.1016/j.ejvs.2018.09.020
  7. Thomas DM, Hulten EA, Ellis ST, Anderson DM, Anderson N, McRae F, et al. Open versus Endovascular Repair of Abdominal Aortic Aneurysm in the Elective and Emergent Setting in a Pooled Population of 37,781 Patients: A Systematic Review and Meta-Analysis. ISRN Cardiol. 2014 Apr;2014:149243. https://doi.org/10.1155/2014/149243
  8. Meuli L, Lattmann T. Versorgungsrealität von Aortenerkrankungen in der Schweiz. Gefasschirurgie. 2021 Jun;26(4):261–9. https://doi.org/10.1007/s00772-021-00782-0
  9. Trenner M, Kuehnl A, Reutersberg B, Salvermoser M, Eckstein HH. Nationwide analysis of risk factors for in-hospital mortality in patients undergoing abdominal aortic aneurysm repair. Br J Surg. 2018 Mar;105(4):379–87. https://doi.org/10.1002/bjs.10714
  10. Trenner M, Salvermoser M, Busch A, Schmid V, Eckstein H-H, Kühnl A. The effects of minimum caseload requirements on management and outcome in abdominal aortic aneurysm repair. Deutsches Aerzteblatt Online. 2020 Nov 27;
  11. Statistik der stationären Betriebe des Gesundheitswesens. Krankenhaustypologie [Internet]. Statistik der stationären Betriebe des Gesundheitswesens. Krankenhaustypologie. 2013. 9 p. (2006). Available from: https://www.bfs.admin.ch/hub/api/dam/assets/169879/master
  12. https://www.pxweb.bfs.admin.ch/pxweb/de/px-x-0102010000_101/-/px-x-0102010000_101.px. Federal Statistical Office - Permanent and non-permanent resident population by institutional units, citizenship (category), sex and age. 2020.
  13. https://www.bfs.admin.ch/bfs/en/home/statistics/population.assetdetail.14367975.html. Federal Statistical Office - Population Data. 2020.
  14. https://www.gbe-bund.de/gbe/pkg_isgbe5.prc_menu_olap?p_uid=gast&p_aid=3767823&p_sprache=D&p_help=0&p_indnr=1000&p_indsp=&p_ityp=H&p_fid=. Gesund¬heits-bericht¬erstat¬tung des Bundes. 2020.
  15. Altman D, Machin D, Bryant T, Gardner M. Statistics with Confidence: Confidence Intervals and Statistical Guidelines, 2nd Edition [Internet]. 2000 [cited 2021 Dec 5]. Available from: https://eprints.soton.ac.uk/393017/
  16. van Walraven C, Austin PC, Jennings A, Quan H, Forster AJ. A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative data. Med Care. 2009 Jun;47(6):626–33. https://doi.org/10.1097/MLR.0b013e31819432e5
  17. R Core Team. (2013). R: A language and environment for statistical computing. URL http://www.R-project.org/. n.d. Vienna, Austria: R Foundation for Statistical Computing; 2013.
  18. Svensjö S, Björck M, Gürtelschmid M, Djavani Gidlund K, Hellberg A, Wanhainen A. Low prevalence of abdominal aortic aneurysm among 65-year-old Swedish men indicates a change in the epidemiology of the disease. Circulation. 2011 Sep;124(10):1118–23. https://doi.org/10.1161/CIRCULATIONAHA.111.030379
  19. Stoberock K, Kölbel T, Atlihan G, Debus ES, Tsilimparis N, Larena-Avellaneda A, et al. Gender differences in abdominal aortic aneurysm therapy - a systematic review. Vasa. 2018 Jun;47(4):267–71. https://doi.org/10.1024/0301-1526/a000703
  20. Powell JT, Hinchliffe RJ, Thompson MM, Sweeting MJ, Ashleigh R, Bell R, et al.; IMPROVE trial investigators. Observations from the IMPROVE trial concerning the clinical care of patients with ruptured abdominal aortic aneurysm. Br J Surg. 2014 Feb;101(3):216–24. https://doi.org/10.1002/bjs.9410
  21. Mandawat A, Mandawat A, Sosa JA, Muhs BE, Indes JE. Endovascular repair is associated with superior clinical outcomes in patients transferred for treatment of ruptured abdominal aortic aneurysms. J Endovasc Ther. 2012 Feb;19(1):88–95. https://doi.org/10.1583/11-3651.1
  22. Scali ST, Beck A, Sedrakyan A, Mao J, Behrendt CA, Boyle JR, et al. Editor’s Choice - Optimal Threshold for the Volume-Outcome Relationship After Open AAA Repair in the Endovascular Era: Analysis of the International Consortium of Vascular Registries. Eur J Vasc Endovasc Surg. 2021 May;61(5):747–55. https://doi.org/10.1016/j.ejvs.2021.02.018
  23. Søgaard R, Lindholt JS. Cost-effectiveness of population-based vascular disease screening and intervention in men from the Viborg Vascular (VIVA) trial. Br J Surg. 2018 Sep;105(10):1283–93. https://doi.org/10.1002/bjs.10872
  24. Thompson SG, Ashton HA, Gao L, Scott RAP. Screening men for abdominal aortic aneurysm: 10 year mortality and cost effectiveness results from the randomised Multicentre Aneurysm Screening Study. BMJ. 2009 Jun 24;338(jun24 2):b2307–b2307.
  25. Wanhainen A, Verzini F, Van Herzeele I, Allaire E, Bown M, Cohnert T, et al.; Esvs Guidelines Committee. Editor’s Choice - European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms. Eur J Vasc Endovasc Surg. 2019 Jan;57(1):8–93. https://doi.org/10.1016/j.ejvs.2018.09.020
  26. Engelberger S, Rosso R, Sarti M, Del Grande F, Canevascini R, van den Berg JC, et al. Ultrasound screening for abdominal aortic aneurysms. Swiss Med Wkly. 2017 Mar;147(0910):w14412.
  27. Landon BE, O’Malley AJ, Giles K, Cotterill P, Schermerhorn ML. Volume-outcome relationships and abdominal aortic aneurysm repair. Circulation. 2010 Sep;122(13):1290–7. https://doi.org/10.1161/CIRCULATIONAHA.110.949172
  28. Cho JS, Kim JY, Rhee RY, Gupta N, Marone LK, Dillavou ED, et al. Contemporary results of open repair of ruptured abdominal aortoiliac aneurysms: effect of surgeon volume on mortality. J Vasc Surg. 2008 Jul;48(1):10–7. https://doi.org/10.1016/j.jvs.2008.02.067
  29. Wanhainen A, Verzini F, Van Herzeele I, Allaire E, Bown M, Cohnert T, et al.; Esvs Guidelines Committee. Editor’s Choice - European Society for Vascular Surgery (ESVS) 2019 Clinical Practice Guidelines on the Management of Abdominal Aorto-iliac Artery Aneurysms. Eur J Vasc Endovasc Surg. 2019 Jan;57(1):8–93. https://doi.org/10.1016/j.ejvs.2018.09.020
  30. Hinchliffe RJ, Ribbons T, Ulug P, Powell JT. Transfer of patients with ruptured abdominal aortic aneurysm from general hospitals to specialist vascular centres: results of a Delphi consensus study. Emerg Med J. 2013 Jun;30(6):483–6. https://doi.org/10.1136/emermed-2012-201239
  31. Meuli L, Zimmermann A, Menges AL, Tissi M, Becker S, Albrecht R, et al. Helicopter emergency medical service for time critical interfacility transfers of patients with cardiovascular emergencies. Scand J Trauma Resusc Emerg Med. 2021 Dec;29(1):168. https://doi.org/10.1186/s13049-021-00981-4

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