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Moderate to Severe Renal Insufficiency Is Associated With High Mortality After Hip and Knee Replacement mydrg.de





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Moderate to Severe Renal Insufficiency Is Associated With High Mortality After Hip and Knee Replacement

Moderate to Severe Renal Insufficiency Is Associated With High Mortality After Hip and Knee Replacement (Ovid).



In patients having elective hip or knee replacements, many comorbid conditions, including diabetes, cardiovascular disease, and congestive heart failure, are associated with postoperative
mortality. Renal failure and a history of renal transplantation also increase mortality. However, the effect of different stages of chronic kidney disease on patients’ prognoses is
unclear.


[...]

Conclusions
All stages of chronic kidney disease have a harmful effect on long-term life expectancy in joint replacement recipients. The risk becomes clinically meaningful in the most severe forms of the disease, but also in moderate chronic kidney disease when it is accompanied by diabetes, coronary disease, or congestive heart failure. It should be recognized that these patients achieve
fewer quality-adjusted life-years even if clinical outcomes were similar. The effect of chronic kidney disease on cost-effectiveness of hip and knee replacements should be investigated in future studies.

[...]

Quelle: Ovid, 01.06.2019

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