Epidemiology of Sepsis Among Children and Neonates in Germany
Epidemiology of Sepsis Among Children and Neonates in Germany - Results From an Observational Study Based on Nationwide Diagnosis-Related Groups Data Between 2010 and 2016 (Critical Care Medicine).
Worldwide, more than half of all sepsis cases occur in pediatric and adolescent patients, particularly in neonates. Previous population-based studies in these age groups often were limited to either neonatal or pediatric patients admitted to ICUs. We aimed to investigate the overall and age-specific
incidence and case fatality of sepsis in children in Germany, [...]
The incidence of pediatric sepsis was 14 cases per 100,000 children between 0
and 19 years. Case fatality was 16.6% and decreased from 17.8% (2010) to 15.0%
(2016). A total of 11.5% of hospital deaths in the age group 0–19 years were
associated with pediatric sepsis.
In neonates, the incidence of neonatal sepsis was 1,006
cases per 100,000 live births. Case fatality was 3.9%. While 17.7% of very low
birth weight infants had neonatal sepsis, only 2.1% of low birth weight and
0.6% of normal birth weight neonates were affected, respectively.
Sepsis is also in Germany a common and frequently fatal condition in pediatric
patients, particularly among neonates and children with comorbidities.
Quelle: Critical Care Medicine, 23.02.2021